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Hydroxyzine side effects

Across 53 first-hand reports, people mentioned a side effect 17 times (about 32 per 100 reports). The most common: drowsiness, vivid dreams, fatigue. User reports show what people notice — they can't tell you whether Hydroxyzine is safe for you.

Reported side effects

drowsiness10
vivid dreams2
fatigue2
brain fog1
zombie1
serotonin syndrome1

In their own words

“I also take naproxil (hyroxyzine) as a prn if I need it, but it's almost like taking a Benadryl. It's more effective with panic than anxiety.”
HelpedRead the discussion ↗
“Over the last few years I've been put on Hydroxyzine, Lexapro, Cymbalta, and Mirtazapine...none helped with anxiety”
Didn't helpRead the discussion ↗
“Hydroxyzine (worked soooo well, but it always makes me dream)”
MixedRead the discussion ↗
“hydroxyzine just makes me feel like a zombie the next day”
Didn't helpRead the discussion ↗
“These definitely knock me out, but I wake up very groggy and am like that for half the next day.”
MixedRead the discussion ↗
“What did me in was a single dose of hydroxyzine mixed with a single dose of sertraline.”
Didn't helpRead the discussion ↗

Is Hydroxyzine safe? What the research covers

AResearch: Strong34 meta-analyses · 166 randomized trials on PubMed
Hum Psychopharmacol · 2023
Efficacy and safety of hydroxyzine for sleep in adults: Systematic review

Conclusion: The studies in this review suggest hydroxyzine could be considered as a short-term treatment option for adults with insomnia for whom previous therapy was ineffective, not tolerated, or contraindicated. Additional long-term studies with an active comparator are needed to further establish its role in insomnia treatment.

Hydroxyzine side effects: what 53 users report — PlainPill