Conclusion: Overall, although limited and requiring interpretation with utmost caution, current evidence indicates that HMB supplementation is beneficial for improving muscle mass and strength, but there is no evidence of a benefit on physical performance in patients with sarcopenia. In future, more well-designed HMB intervention trials should be conducted that include populations diagnosed with sarcopenia according to well-accepted clinical consensus.
Does HMB help with performance?
Possibly — but there are few reports. 100% of 6 people who reported on HMB for performance say it improved. 0% noticed no change and 0% say it got worse.
Performance: what users report
100%better6 reports · few reports
6 better0 no change0 worse
What people say about HMB and performance
“I started HMB/creatine and stopped most of the cardio and had an immediate benefit of gaining muscle mass while losing further body fat.”
“I'm mid fifties and on a lower calorie keto diet and I'm building muscle.”
“Creatine, hmb and betaine has been working pretty good for me.”
“I would supplement with both HMB and L-carnosine”
What the research says
AResearch: Strong120 meta-analyses · 192 trials on PubMed
Maturitas · 2025
The effects of β-hydroxy-β-methylbutyrate supplementation in patients with sarcopenia: A systematic review and meta-analysisJ Cachexia Sarcopenia Muscle · 2022
Effects of β-hydroxy β-methylbutyrate (HMB) supplementation on muscle mass, function, and other outcomes in patients with cancer: a systematic reviewConclusion: Although limited, current evidence suggests that HMB supplementation has a beneficial effect on muscle mass and function in patients with cancer. Well-designed trials are needed to further explore the clinical benefit of HMB supplementation in this patient population.
Am J Clin Nutr · 2019
β-Hydroxy-β-methylbutyrate and its impact on skeletal muscle mass and physical function in clinical practice: a systematic review and meta-analysisSide effects people mention
anger 1weird feeling 1
What else is HMB used for?
Based on few reports — treat as anecdotal. Information only — not medical advice. How we count