Conclusion: Different interventions (GABA-analogues, kappa-opioid receptor agonists, cromolyn sodium, montelukast, fish-oil/omega-3 fatty acids and topical capsaicin compared to placebo) were effective for uraemic pruritus. GABA-analogues had the largest effect on pruritus. Rifampin, naltrexone and flumecinol tended to be effective for cholestatic pruritus. However, therapies for patients with malignancies are still lacking. Due to the small sample sizes in most meta-analyses and the heterogeneous methodological quality of the included trials, the results should be interpreted cautiously in terms of gener
PubMed 37314034 ↗Fish Oil Omega 3
People mainly take Fish Oil Omega 3 for pain & inflammation, focus, mood. Based on 11 first-hand reports and 6 meta-analyses & systematic reviews in the medical literature. Ranked #1681 of 4,149 overall.
Of reports that state an outcome, 50% are positive.
What Fish Oil Omega 3 does, according to users
Of the people who reported each effect, the share who said it got better.
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Vitamin B1 is shown to be an effective treatment for dysmenorrhoea taken at 100 mg daily, although this conclusion is tempered slightly by its basis on only one large RCT. Results suggest that magnesium is a promising treatment for dysmenorrhoea. It is unclear what dose or regime of treatment should be used for magnesium therapy, due to variations in the included trials, therefore no strong recommendation can be made until further evaluation is carried out. Overall there is insufficient evidence to recommend the use of any of the other herbal and dietary therapies considered in this review for
PubMed 11687013 ↗Conclusion: Omega-3 Fatty acids may be beneficial and should be considered in patients with documented coronary heart disease. They may be particularly beneficial for patients with risk factors for sudden cardiac death.
PubMed 12452760 ↗Conclusion: Considering behavioral parameters, pathological markers of the disease, quantification of ω-3 PUFAs in the brain, as well as anti-inflammatory, antioxidant, and anti-apoptotic effects, it can be observed that ω-3 PUFAs exhibit a potential neuroprotective effect in PD. In summary, this systematic review presents significant scientific evidence regarding the effects and mechanisms underlying the neuroprotective properties of ω-3 PUFAs, offering valuable insights for the development of future clinical investigations.
PubMed 38923542 ↗Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.
“Omega 3 without a doubt. Does wonders for my mood, confidence and motivation. ... I take 3g daily of an EPA-favored.”
“I've heard this is healthy and everyone should take it, but to be honest I haven't noticed much personally from it”
“In 2016 I took Omega 3 gel capsules, instantly got worse brain fog, couldn't think straight”
Top discussions (5)
- This stack is perfect for me ↗
- Rating every nootropic I've taken ↗
- This may be off topic, but what do you think of Ray Kurzweil and his quest to live forever? ↗
- Omega-3 has beneficial effects on cognitive function and could be helpful as a preventive or therapeutic tool in older adults, according to a review of 14 randomized controlled trials. Learn more omega-3 science in this comprehensive 30-page article from FoundMyFitness (Rhonda Patrick's website) ↗
- Help me fix a lifetime of damage ↗
Other options for pain & inflammation
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate