Across 73 first-hand reports, people mentioned a side effect 7 times (about 10 per 100 reports). The most common: vivid dreams, night sweats, loose stools. User reports show what people notice — they can't tell you whether Fisetin is safe for you.
“I overdosed on Fisetin in January of this year and am getting side effects up to now. I had 60 capsules in one sitting and I also had 10 ultra strength ones(so equivallent of 18g).”
“I'm 28 and take courses of fisetin at 20 mg/kg/day x 2 days to prevent senescent cell accumulation. I've had no side effects.”
“I noticed my sleep has been really deep but also coupled with intense intense dreams... Only negative so far is some loose stools that are much darker than normal... Overall feeling pretty tired”
“That included compounds such as: Niacin, NMN, Apigenin, Quercetin, Fisetin...my liver tests came back to normal after 8 weeks.”
Conclusion: Fisetin, by antioxidant, anti-inflammatory, mitochondrial protection, promoting autophagy, and anti-apoptotic properties, can reduce cell injury due to myocardial, cerebral renal, and hepatic IRIs without any significant side effects.
Conclusion: A total of 21, 15 and 7 pre-clinical articles on bladder or prostate cancer reporting on kaempferol, fisetin and myricetin, respectively, were found, while more limited evidence was available from animal models and epidemiological studies or clinical trials. In conclusion, the available evidence supports the potential use of these flavonols in prostate and bladder cancer, with a low expected toxicity, thus providing the rationale for clinical trials that explore dosing, settings for clinical use as well as their use in combination with other pharmacological and non-pharmacological intervention