PlainPill

Does Enclomiphene help with hormones?

Yes, for most people. 90% of 137 people who reported on Enclomiphene for hormones say it improved. 2% noticed no change and 8% say it got worse. That is above the typical result for hormones (85% across 24 options).

Hormones: what users report
90%better137 reports · high confidence
123 better3 no change11 worse

Ranked #3 of 24 for hormones.

What people say about Enclomiphene and hormones

“I felt like I was sleeping better, had more energy, more confidence, and more libido.”
Read the discussion ↗
“My Testosterone roughly doubled, but my Estrogen roughly tripled, and while I got an initial feel-good period, it dwindled away after a couple of weeks.”
Read the discussion ↗
“3mg enclo squad here too, it's amazing how much such a small dose can do, feel hornier and my nuts are clearly more active than off-cycle.”
Read the discussion ↗
“when I take enclo at just 6.25mg ED my libido goes as soon as I feel better from the enclo.”
Read the discussion ↗

What the research says

BResearch: Moderate2 meta-analyses · 3 trials on PubMed
Arch Endocrinol Metab · 2025
Clomiphene or enclomiphene citrate for the treatment of male hypogonadism: a systematic review and meta-analysis of randomized controlled trials

Conclusion: SERM therapy is associated with significantly improved levels of TT, LH, and FSH in hypogonadal men compared to placebo, and significantly enhanced levels of LH and FSH compared to T gel. The findings suggest that SERM therapy effectively increases TT levels in men with functional hypogonadism and should be considered as an alternative to T gel therapy.

Andrology · 2023
Selective modulation of estrogen receptor in obese men with androgen deficiency: A systematic review and meta-analysis

Conclusion: Treatment with clomiphene citrate and enclomiphene citrate may be an effective and safe alternative to testosterone replacement therapy in men with obesity-related functional androgen deficiency. Further long-term studies are warranted to define clinical reflections of the selective estrogen receptor modulators-induced increase in testosterone levels and to better clarify the safety profile.

Side effects people mention

eye floaters 9vision issues 5mood swings 4hair loss 4blurry vision 3

What else is Enclomiphene used for?

Information only — not medical advice. How we count

Does Enclomiphene help with hormones? 90% of 137 users say yes — PlainPill