PlainPill

Dnp

People mainly take Dnp for weight loss, heart & lipids. Based on 13 first-hand reports and 55 meta-analyses & systematic reviews in the medical literature. Ranked #872 of 3,539 overall.

25
User score
Mostly positive
31% positive8% mixed8% negative54% unclear

Of reports that state an outcome, 66% are positive.

Clinical research
AStrong research base
55
meta-analyses
22
RCTs
9,023
papers

What Dnp does, according to users

Of the people who reported each effect, the share who said it got better.

1 more with fewer than 3 reports
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

AANA J · 2021 · Meta-analysis / systematic review
Supplemental Oxygen and Surgical Site Infection in Colorectal Surgery: A Systematic Review and Meta-analysis

Conclusion: Conversely, we found low quality evidence of no effect on length of stay measured in days (MD, 0.39; 95% CI -0.59 to 1.36; P = 0.44). Although additional studies are required to decrease heterogeneity of the studies, the current review showed high FiO2 does not decrease the incidence of SSI in the colorectal surgery population.

PubMed 34042576 ↗
J Addict Nurs · 2016 · Meta-analysis / systematic review
Combating Opioid Overdose With Public Access to Naloxone

Conclusion: Although many authors have researched and discussed public naloxone distribution, a comprehensive review of the current evidence is useful and necessary to enhance future research, practice, and policy efforts. By discovering significant gaps in the literature and by recognizing opportunities for nursing practice, this literature review provides valuable input for healthcare professionals, public health officials, policymakers, and laypersons to better understand an ethically, politically, and socially complicated public health initiative.

PubMed 27580190 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

never more than 3 weeks at a timeas reported

Reported side effects

How often each side effect came up across all reports.

death ×2heart problems ×1metabolic disorders ×1hormone disruption ×1hpa axis ×1sweating ×1night sweats ×1shortness of ×1

What users say

First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.

Other options for weight loss

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate