PlainPill

Dmaa

People mainly take Dmaa for energy, focus, performance. Based on 11 first-hand reports and 9 meta-analyses & systematic reviews in the medical literature. Ranked #945 of 1,974 overall.

15
User score
Mixed
9% positive18% mixed18% negative55% unclear

Of reports that state an outcome, 20% are positive.

Clinical research
BModerate research base
9
meta-analyses
8
RCTs
595
papers

What Dmaa does, according to users

Of the people who reported each effect, the share who said it got better.

2 more with fewer than 3 reports
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

BModerate research base

At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.

Cochrane Database Syst Rev · 2004 · Meta-analysis / systematic review
Memantine for dementia

Conclusion: :Memantine 20 mg/day caused a clinically noticeable reduction in deterioration over 28 weeks in patients with moderate to severe Alzheimer disease. This was supported by less functional and cognitive deterioration. Patients taking memantine were less likely to become agitated. The effect in mild to moderate AD is unknown. Patients with mild to moderate vascular dementia receiving memantine 20 mg/day had less cognitive deterioration at 28 weeks but the effects were not clinically discernible. There is an early beneficial effect on cognition, mood, behaviour and clinical impression for memantine

PubMed 15495043 ↗
Cochrane Database Syst Rev · 2003 · Meta-analysis / systematic review
Memantine for dementia

Conclusion: There is a beneficial effect of memantine (20 mg/day) for patients with moderate to severe Alzheimer disease on cognition and functional decline but not in the clinical impression of change. Patifor patients with moderate to severe Alzheimer disease on cognition and functional decline but not in the clinical impression of change. Patients with mild to moderate vascular dementia receiving memantine 20 mg/day had less cognitive deterioration at 28 weeks but again this effect was not clinically discernible. There is a possible beneficial effect on cognition, function and global scales for memanti

PubMed 12917950 ↗
Cochrane Database Syst Rev · 2003 · Meta-analysis / systematic review
Memantine for dementia

Conclusion: Memantine is a safe drug and may be useful for treating Alzheimer's, vascular,and mixed dementia of all severities. Most of the trials so far reported have been small and not long enough to detect clinically important benefits. However there is a possible benefit on cognition and global measures, and an early improvement in behaviour in people with dementia. More studies are needed.

PubMed 12535459 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

25 mgas reported
25-75 mg3x week
50 mgas reported

Reported side effects

How often each side effect came up across all reports.

cardiac stimulation ×1jitteriness ×1heart attack ×1fatigue ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“DMAA”
Source discussion ↗
“More like 20% of Adderall's cognitive enhancement and 150% of its side effects”
Source discussion ↗
“Our DMAA bottles use a 25mg dosage for focus.”
Source discussion ↗
“DMAA, 3x week, starting at 25mg for the first week 50mg for the second, and 75 for the third week”
Source discussion ↗
Top discussions (5)

Other options for energy

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate