PlainPill

Chromium Picolinate

People mainly take Chromium Picolinate for appetite, blood sugar. Based on 5 first-hand reports and 14 meta-analyses & systematic reviews in the medical literature. Ranked #1407 of 3,539 overall.

20
User score
Mostly positive
40% positive0% mixed0% negative60% unclear

Of reports that state an outcome, 100% are positive.

Clinical research
AStrong research base
14
meta-analyses
59
RCTs
420
papers

What Chromium Picolinate does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

Environ Geochem Health · 2024 · Meta-analysis / systematic review
Chromium supplementation and type 2 diabetes mellitus: an extensive systematic review

Conclusion: However, most research findings include significant limitations, such as inconsistent dosage and type of chromium, formulation of supplements, and study duration. Further well-designed and high-quality research is needed to fully understand the role of chromium dietary supplementation and the potential risks related to its mechanisms of action, type, and dose, in the prevention and treatment of type 2 diabetes mellitus.

PubMed 39541030 ↗
J Clin Pharm Ther · 2014 · Meta-analysis / systematic review
Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes

Conclusion: The available evidence suggests favourable effects of chromium supplementation on glycaemic control in patients with diabetes. Chromium monosupplement may additionally improve triglycerides and HDL-C levels. Chromium supplementation at usual doses does not increase the risk of adverse events compared with placebo. Data on chromium combined supplementation are limited and inconclusive. Long-term benefit and safety of chromium supplementation remain to be further investigated.

PubMed 24635480 ↗
Biol Trace Elem Res · 2019 · Meta-analysis / systematic review
Systematic Review of the Effects of Chromium(III) on Chickens

Conclusion: Few potential trends in terms or beneficial or deleterious effects from Cr supplementation were found regardless of strain of chicken, Cr source, Cr dose, duration of supplementation, or variable examined. Hence, in summary, no recommendation for the use of Cr as a supplement for the diet of chickens can be made at this time.

PubMed 30430417 ↗
Cochrane Database Syst Rev · 2018 · Meta-analysis / systematic review
Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment

Conclusion: The evidence on vitamin and mineral supplements as treatments for MCI is very limited. Three years of treatment with high-dose vitamin E probably does not reduce the risk of progression to dementia, but we have no data on this outcome for other supplements. Only B vitamins have been assessed in more than one RCT. There is no evidence for beneficial effects on cognition of supplementation with B vitamins for six to 24 months. Evidence from a single study of a reduced rate of brain atrophy in participants taking vitamin B and a beneficial effect of vitamin B on episodic memory in those with high

PubMed 30383288 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

1500 ugas reported
dailyas reported
200 mcgdaily
small dosesas reported

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.

Other options for appetite

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate