PlainPill
SupplementMoodFocusMemory

Celastrus

The short answer. There isn't much data on Celastrus yet — 9 mentions, 4 with a clear outcome — so treat these numbers as anecdotal. There is a moderate body of research — 1 meta-analyses and 0 trials.

Compare with…Alternatives for mood
What users report
75%helped4 reports · few reports
3 helped1 mixed0 didn't help

From 9 mentions in total — the rest didn't say how it went and aren't counted.

Clinical research
BModerate research base
1
meta-analyses
0
RCTs
320
papers

What Celastrus does, according to users

Of the people who reported each effect, the share who said it got better.

Mood100% of 2Focus100% of 1Memory100% of 1
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

BModerate research base

At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.

Phytother Res · 2026 · Meta-analysis / systematic review
Celastrus paniculatus Willd.: An Extensive Review of Phytochemistry, Traditional Uses, Pharmacological Potential, and Safety Profile

Conclusion: Despite compelling preclinical evidence, randomized controlled trials in humans are currently absent. Future research should focus on clinical validation, standardization of phytopharmaceutical quality, and translational strategies to facilitate its evidence-based incorporation into contemporary healthcare systems.

PubMed 41920476 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

No doses stated in the reports so far.

Reported side effects

How often each side effect came up across all reports.

headache ×1

What users say

First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.

“Celastrus is pretty damn good for creativity as well. It's maybe one of the strongest neruotrophic inducers...after two weeks it actually help in growing more dandrites...I feel nice mood boost and emotionally healthy”
HelpedRead the discussion ↗
“a week later I realized I was remembering stuff better”
MixedRead the discussion ↗
“I've had considerable result with this stack, though, a bit inconsistent.”
HelpedRead the discussion ↗
Top discussions (5)

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User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate