What are the side effects of Baclofen?

Users most often report withdrawal, dizziness, hallucinations, insomnia, agitation. Side effects came up 9 times across 68 reports.

User reports can't establish safety. PubMed lists 168 meta-analyses and 214 randomized trials. Talk to a doctor or pharmacist, especially if you take other medication.

Baclofen side effects

Across 68 first-hand reports, people mentioned a side effect 9 times (about 13 per 100 reports). The most common: withdrawal, dizziness, hallucinations. User reports show what people notice — they can't tell you whether Baclofen is safe for you.

Reported side effects

withdrawal2

dizziness1

hallucinations1

insomnia1

agitation1

depression1

possible impaired1

anxiety1

In their own words

“It works well. Currently taking 20mg/day, but will have to increase because I am not quite satisfied with the results. Having said that, I feel a little dizzy even on 20mg.”

MixedRead the discussion ↗

“I tried Baclofen/phenibut too which is supposed to help autistic people with empathy, but i felt zero difference.”

Didn't helpRead the discussion ↗

“The baclofin made my Benzo taper extremely manageable and I ended up really liking the way gaba b agonist made me feel”

MixedRead the discussion ↗

“I was taking about 40mgs of baclofen a day but that quickly got to 80mgs, just barely keeping the gaba-b withdrawals away...withdrawals from baclofen would start within 3 hours.”

MixedRead the discussion ↗

Is Baclofen safe? What the research covers

AResearch: Strong168 meta-analyses · 214 randomized trials on PubMed

J Addict Med · 2022

Pharmacotherapies for Adults With Alcohol Use Disorders: A Systematic Review and Network Meta-analysis

Conclusion: The current meta-analyses provide evidence that several medications for AUDs are effective and safe and encourage the expanded use of these medications in the clinical setting. Our review found that acamprosate (2-3 g/d), disulfiram (250-500 mg/d), baclofen (30 mg/d), and oral naltrexone (50 mg/d) had the best evidence for improving abstinence and heavy drinking for patients with AUD.

BMJ Clin Evid · 2014

Dystonia

Conclusion: In this systematic review, we present information relating to the effectiveness and safety of the following interventions: acupuncture, amantadine, baclofen, benzatropine, biofeedback, botulinum toxins, bromocriptine, carbamazepine, carbidopa/levodopa, clonazepam, clozapine, deep brain stimulation of thalamus and globus pallidus, diazepam, gabapentin, haloperidol, lorazepam, myectomy (for focal dystonia), occupational therapy, ondansetron, physiotherapy, pregabalin, procyclidine, selective peripheral denervation (for focal dystonia), speech therapy, tizanidine, trazodone hydrochloride, and tri

BMJ · 2023

Comparative effectiveness and safety of analgesic medicines for adults with acute non-specific low back pain: systematic review and network meta-analysis