Conclusion: Some medications could improve core symptoms, although this could be likely secondary to the improvement of associated symptoms. Evidence on their efficacy and safety is preliminary; therefore, routine prescription of medications for the core symptoms cannot be recommended. Trial registration PROSPERO-ID CRD42019125317.
Aripiprazole side effects
Across 37 first-hand reports, people mentioned a side effect 8 times (about 22 per 100 reports). The most common: weight gain, brain fog, fatigue. User reports show what people notice — they can't tell you whether Aripiprazole is safe for you.
Reported side effects
weight gain2
brain fog2
fatigue1
sexual dysfunction1
unspecified side1
insomnia1
What got worse for some people
In their own words
“I have given very few of them fair trials, as I can't deal with the side effects for that long.”
“it made me feel sedative and made ADHD symptoms worse, so I stopped taking it”
“I couldn't really take it...made my tight pelvic floor much worse, I could only pee once or twice a day”
“I take abilify which messes with my metabolism and causes weight gain.”
“I'm currently on a low dose (2 mg) and yes, ruminations are diminished if not outright eliminated.”
“The single best thing for my brain fog was Aripiprazole... it improves mental clarity. I'm on 5MGs currently.”
Is Aripiprazole safe? What the research covers
AResearch: Strong459 meta-analyses · 424 randomized trials on PubMed
Mol Autism · 2022
Pharmacological and dietary-supplement treatments for autism spectrum disorder: a systematic review and network meta-analysisEur Neuropsychopharmacol · 2024
Efficacy, acceptability and side-effects of oral versus long-acting- injectables antipsychotics: Systematic review and network meta-analysisConclusion: LAIs are efficacious for acute schizophrenia and may have some benefits compared to oral formulations in terms of side effects. These findings assist clinicians with insights to weigh the risks and benefits between oral and injectable agents when treating patients in the acute phase.