PlainPill

Omega-3 vs TB-500 for pain & inflammation

Short answer: For pain & inflammation, more users report improvement with Omega-3 — 91% of 82 reports, versus 84% of 168 for TB-500.

Omega-3 has 1,341 meta-analyses and 3,093 randomized trials on PubMed; TB-500 has 0 and 3.

Based on 1,959 reports about Omega-3 and 652 about TB-500. Not medical advice.

Omega-3
Supplement
TB-500
Peptide
User score4749
Verdict
Mostly positive
Mostly positive
Positive
of reports that state an outcome
66%67%
Reports1,959652
ResearchAResearch: StrongCResearch: Limited
Meta-analyses / RCTs1,341 / 3,0930 / 3
Mainly used for
Weight loss
% reporting improvement
100% (2)100% (8)
Appetite
% reporting improvement
—100% (2)
Focus
% reporting improvement
82% (129)50% (2)
Energy
% reporting improvement
74% (42)50% (4)
Sleep
% reporting improvement
79% (24)60% (5)
Anxiety
% reporting improvement
75% (69)29% (7)
Mood
% reporting improvement
82% (201)89% (9)
Memory
% reporting improvement
78% (50)—
Performance
% reporting improvement
88% (16)100% (17)
Recovery
% reporting improvement
90% (20)97% (208)
Pain & inflammation
% reporting improvement
91% (82)84% (168)
Digestion
% reporting improvement
22% (9)100% (2)
Libido
% reporting improvement
71% (14)—
Hormones
% reporting improvement
100% (2)—
Blood sugar
% reporting improvement
50% (2)—
Heart & lipids
% reporting improvement
76% (58)60% (5)
Skin & hair
% reporting improvement
89% (38)84% (19)
Immunity
% reporting improvement
60% (10)60% (5)
Longevity
% reporting improvement
86% (7)—
Common side effectsbrain fog, anxiety, depression, fatigueanxiety, fatigue, dizziness, allergic reaction
Typical dose reportedsparinglyNot listed
Omega-3
Latest review conclusion

For glycated hemoglobin, there was no significant effect in the meta-analysis. This systematic review with meta-analysis demonstrated that supplementation with omega-3 has protective effects on diabetes parameters.

Crit Rev Food Sci Nutr, 2022 ↗
What a user said
“I do supplement a lot of fish oil and vitamin A as retinyl palmitate though. It has really helped my depression, anxiety and ADHD and has enabled me to stop using more serious psychiatric drugs for those things.”
Full Omega-3 profile →
TB-500
What a user said
“They reduce neuroinflammation in the brain caused by either head injuries or drug abuse. Ive used them both for this and it works.”
Full TB-500 profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate