PlainPill

L-Arginine vs L-Carnitine for performance

Short answer: For performance, more users report improvement with L-Carnitine — 92% of 13 reports, versus 83% of 12 for L-Arginine.

L-Arginine has 106 meta-analyses and 765 randomized trials on PubMed; L-Carnitine has 170 and 466.

Based on 211 reports about L-Arginine and 195 about L-Carnitine. Not medical advice.

L-Arginine
Supplement
L-Carnitine
Supplement
Users say it helped49%helped78 reports · medium confidence61%helped55 reports · medium confidence
Verdict
Mixed
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs106 / 765170 / 466
Mainly used for
Libido
% reporting improvement
88% (41)—
Performance
% reporting improvement
83% (12)92% (13)
Energy
% reporting improvement
—96% (23)
Weight loss
% reporting improvement
0% (2)67% (18)
Heart & lipids
% reporting improvement
86% (14)0% (2)
Common side effectsdiarrhea, stomach issues, chest pain, tongue bitinginjection pain, insomnia, tingling, lowered thyroid
Typical dose reported2 g / before bed2 g / daily
L-Arginine
Latest review conclusion

Supplementation of some but not all micronutrients may benefit cardiometabolic health. This study highlights the importance of micronutrient diversity and the balance of benefits and risks to promote and maintain cardiovascular health in diverse populations. (Antioxidant Supplementation in the Prevention and Treatment of Cardiovascular Diseases; CRD42022315165).

J Am Coll Cardiol, 2022 ↗
What a user said
“Something I found that makes my meds work way better is Citrulline 2g + Arginine 2g twice daily.”
Full L-Arginine profile →
L-Carnitine
Latest review conclusion

l-carnitine supplementation provides a modest reducing effect on body weight, BMI and fat mass, especially among adults with overweight/obesity.

Clin Nutr ESPEN, 2020 ↗
What a user said
“amino acids L carnitine and glutamine made a difference in my skin.”
Full L-Carnitine profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate