Curcumin vs Rapamycin for longevity
Short answer: For longevity, users rate them about the same: 100% report improvement with Curcumin (6 reports) and 100% with Rapamycin (7 reports).
Curcumin has 538 meta-analyses and 553 randomized trials on PubMed; Rapamycin has 497 and 1,245.
Based on 544 reports about Curcumin and 61 about Rapamycin. Not medical advice.
| Curcumin Supplement | Rapamycin Medication | |
|---|---|---|
| Users say it helped | 61%helped180 reports · high confidence | 28%helped11 reports · few reports |
| Verdict | Mostly positive | Mixed |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 538 / 553 | 497 / 1,245 |
| Mainly used for | ||
| Pain & inflammation % reporting improvement | 91% (104) | — |
| Mood % reporting improvement | 96% (45) | 100% (2) |
| Anxiety % reporting improvement | 93% (15) | — |
| Longevity % reporting improvement | 100% (6) | 100% (7) |
| Memory % reporting improvement | 100% (12) | — |
| Common side effects | vivid dreams, headache, nausea, dht suppression | fatigue, slow wound, canker sores, hyperglycemia |
| Typical dose reported | 1000 mg / daily | Not listed |
Curcumin and Curcuma longa Extract may improve symptoms and inflammation levels in people with arthritis. However, due to the low quality and small quantity of RCTs, the conclusions need to be interpreted carefully.
Front Immunol, 2022 ↗“I recently stopped taking Curcumin because of its affect on DHT and I was looking for an alternative measure to deal with inflammation as I feel it really helped with anxiety/depression.”
The majority of the patients reported adverse events limited to grade 1 or 2. On the whole, the data presented herein confirm the findings of previous studies on the relative safety of everolimus, a targeted therapeutic agent, which differs from that of conventional chemotherapy, and highlight the potential adverse events associated with the therapeutic use of everolimus.
Int J Oncol, 2021 ↗“I've noticed a 10% increase in HDL and some fatigue the day after taking more than 6mg.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate