COQ10 vs L-Citrulline for heart & lipids
Short answer: For heart & lipids, more users report improvement with COQ10 — 100% of 21 reports, versus 95% of 22 for L-Citrulline.
COQ10 has 176 meta-analyses and 405 randomized trials on PubMed; L-Citrulline has 14 and 101.
Based on 713 reports about COQ10 and 231 about L-Citrulline. Not medical advice.
| COQ10 Supplement | L-Citrulline Supplement | |
|---|---|---|
| Users say it helped | 65%helped164 reports · high confidence | 77%helped99 reports · medium confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 176 / 405 | 14 / 101 |
| Mainly used for | ||
| Energy % reporting improvement | 93% (97) | 100% (11) |
| Performance % reporting improvement | 100% (7) | 98% (45) |
| Libido % reporting improvement | 100% (3) | 98% (48) |
| Heart & lipids % reporting improvement | 100% (21) | 95% (22) |
| Focus % reporting improvement | 68% (19) | 67% (3) |
| Common side effects | aggression, brain fog, skin rash, stomach issues | cold sore, dizziness, headache, increased urination |
| Typical dose reported | 200 mg | 8 g / 3x/week |
These findings suggested that CoQ10 pretreatment is an effective intervention in improving IVF/ICSI outcomes for women with DOR. Still, this meta-analysis included relatively limited sample sizes with poor descriptions of their methodologies. Rigorously conducted trials are needed in the future.
Ann Med, 2024 ↗“I rely on 200mg of Qunol Co-enzyme Q10 to take with my 40mg of Crestor to prevent statin side effects. Works wonderfully.”
Foods rich in polyphenols and nitrate provide trivial benefits for endurance exercise performance, although these effects may be food dependent. Highly trained endurance athletes do not appear to benefit from consuming nitrate-rich foods but may benefit from polyphenol consumption. Further research into food sources, dosage and supplementation duration to optimise the ergogenic response to polyphenol consumption is warranted. Further studies should evaluate whether differential sex-based responses to nitrate and polyphenol consumption are attributable to physiological differences or sample siz
J Int Soc Sports Nutr, 2021 ↗“Something I found that makes my meds work way better is Citrulline 2g + Arginine 2g twice daily.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate