PlainPill

Black Seed Oil vs TB-500 for pain & inflammation

Short answer: For pain & inflammation, more users report improvement with Black Seed Oil — 100% of 17 reports, versus 86% of 199 for TB-500.

Black Seed Oil has 2 meta-analyses and 9 randomized trials on PubMed; TB-500 has 0 and 3.

Based on 279 reports about Black Seed Oil and 874 about TB-500. Not medical advice.

Black Seed Oil
Supplement
TB-500
Peptide
Users say it helped66%helped114 reports · high confidence65%helped402 reports · high confidence
Verdict
Mostly positive
Mostly positive
ResearchBResearch: ModerateCResearch: Limited
Meta-analyses / RCTs2 / 90 / 3
Mainly used for
Recovery
% reporting improvement
100% (2)96% (297)
Pain & inflammation
% reporting improvement
100% (17)86% (199)
Anxiety
% reporting improvement
94% (52)29% (7)
Mood
% reporting improvement
90% (39)91% (11)
Skin & hair
% reporting improvement
75% (4)88% (25)
Common side effectsstomach issues, nausea, oily skin, heartburnanxiety, fatigue, dizziness, allergic reaction
Typical dose reported1 teaspoon / dailyNot listed
Black Seed Oil
Latest review conclusion

Nigella sativa was shown to significantly improve laboratory parameters of hyperglycemia and diabetes control after treatment with a significant fall in fasting blood glucose, blood glucose level 2 h postprandial, glycated hemoglobin, and insulin resistance, and a rise in serum insulin. In conclusion, these findings suggested that Nigella sativa could be used as an adjuvant for oral antidiabetic drugs in diabetes control.

Int J Environ Res Public Health, 2019 ↗
What a user said
“Black seed yes. I'm taking capsules of both strengths. I was hoping it would help with exczema/skin health. But so far it's mainly good for immunity, anxiety. Good all rounder but not sure I'll get it again.”
Full Black Seed Oil profile →
TB-500
What a user said
“They reduce neuroinflammation in the brain caused by either head injuries or drug abuse. Ive used them both for this and it works.”
Full TB-500 profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate