B1 vs Vitamin B6 for energy
Short answer: For energy, more users report improvement with Vitamin B6 — 78% of 23 reports, versus 50% of 2 for B1.
Vitamin B6 has 152 meta-analyses and 261 randomized trials on PubMed; the other has not been graded.
Based on 16 reports about B1 and 522 about Vitamin B6. Not medical advice.
| B1 Supplement | Vitamin B6 Supplement | |
|---|---|---|
| Users say it helped | 39%helped5 reports · few reports | 53%helped157 reports · high confidence |
| Verdict | Mostly negative | Mixed |
| Research | Not graded | AResearch: Strong |
| Meta-analyses / RCTs | — | 152 / 261 |
| Mainly used for | ||
| Hormones % reporting improvement | — | 89% (35) |
| Mood % reporting improvement | — | 91% (33) |
| Sleep % reporting improvement | — | 73% (26) |
| Energy % reporting improvement | 50% (2) | 78% (23) |
| Anxiety % reporting improvement | — | 64% (22) |
| Common side effects | fatigue, brain fog | neuropathy, numbness, vivid dreams, anxiety |
| Typical dose reported | 500 mg / daily | 25 mg / each morning |
B1Full B1 profile →
What a user said
“Once I got my B1 levels back up, I was able to eat carbs and sugars again without getting crazy blood sugar spikes.”
Vitamin B6Full Vitamin B6 profile →
Latest review conclusion
Further, only one study reported effects on idiopathic fatigue, and therefore, no analysis was possible. Vitamin B12 supplementation is likely ineffective for improving cognitive function and depressive symptoms in patients without advanced neurological disorders.
Nutrients, 2021 ↗What a user said
“But that pain gets significantly better when I take glycine, vitamin C and B6 together.”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate