PlainPill

B1 vs Vitamin B12 for energy

Short answer: For energy, more users report improvement with Vitamin B12 — 90% of 103 reports, versus 50% of 2 for B1.

Vitamin B12 has 376 meta-analyses and 572 randomized trials on PubMed; the other has not been graded.

Based on 16 reports about B1 and 630 about Vitamin B12. Not medical advice.

B1
Supplement
Vitamin B12
Supplement
Users say it helped39%helped5 reports · few reports66%helped202 reports · high confidence
Verdict
Mostly negative
Mostly positive
ResearchNot gradedAResearch: Strong
Meta-analyses / RCTs—376 / 572
Mainly used for
Energy
% reporting improvement
50% (2)90% (103)
Mood
% reporting improvement
—89% (46)
Anxiety
% reporting improvement
—62% (21)
Focus
% reporting improvement
—88% (17)
Sleep
% reporting improvement
—42% (12)
Common side effectsfatigue, brain fogacne, anxiety, jitteriness, weakness
Typical dose reported500 mg / daily1 ml
B1
What a user said
“Once I got my B1 levels back up, I was able to eat carbs and sugars again without getting crazy blood sugar spikes.”
Full B1 profile →
Vitamin B12
Latest review conclusion

Subgroup analyses indicated that the use of vitamin B12 supplements among vegans contributes to significant improvements in all biomarker concentrations compared to their unsupplemented counterparts. Our findings underscore the need for improved strategies to redress poor vitamin B12 status with appropriate B12 supplementation use among those adhering to vegetarian and vegan diets.

Nutr Bull, 2024 ↗
What a user said
“I supplemented with sublingual b12 and iron and daily electrolytes and I'm feeling much better.”
Full Vitamin B12 profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate