PlainPill

B Complex vs Multivitamin for energy

Short answer: For energy, more users report improvement with B Complex — 95% of 93 reports, versus 78% of 23 for Multivitamin.

B Complex has 246 meta-analyses and 106 randomized trials on PubMed; the other has not been graded.

Based on 572 reports about B Complex and 765 about Multivitamin. Not medical advice.

B Complex
Supplement
Multivitamin
Supplement
Users say it helped66%helped166 reports · high confidence41%helped130 reports · high confidence
Verdict
Mostly positive
Mixed
ResearchAResearch: StrongNot graded
Meta-analyses / RCTs246 / 106—
Mainly used for
Energy
% reporting improvement
95% (93)78% (23)
Mood
% reporting improvement
91% (35)70% (10)
Focus
% reporting improvement
84% (25)80% (5)
Anxiety
% reporting improvement
43% (23)—
Sleep
% reporting improvement
64% (11)60% (5)
Common side effectsanxiety, insomnia, headache, neuropathystomach issues, nausea, insomnia, toxicity
Typical dose reported500 mcg B12—
B Complex
Latest review conclusion

This meta-analysis suggests that B vitamin supplementation is associated with slowing of cognitive decline, especially in populations who received early intervention and intervention of long duration; the study also indicates that higher intake of dietary folate, but not B12 or B6, is associated with a reduced risk of incident dementia in non-dementia aged population. Given the prevalence of dementia cases in many countries with aging populations, public health policies should be introduced to ensure that subgroups of the population at risk have an adequate B vitamin status.

Nutr Rev, 2022 ↗
What a user said
“Adding a B complex has totally eliminated my depression lethargy brain fog insomnia and anxiety.”
Full B Complex profile →
Multivitamin
What a user said
“I have a stack of supplements that I take specifically for recovery from the adderall and vyvanse that I researched thoroughly, and see huge positive results from.”
Full Multivitamin profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate