PlainPill

Aniracetam vs L-Theanine for anxiety

Short answer: For anxiety, users rate them about the same: 92% report improvement with Aniracetam (191 reports) and 91% with L-Theanine (1289 reports).

Aniracetam has 1 meta-analyses and 9 randomized trials on PubMed; L-Theanine has 18 and 78.

Based on 899 reports about Aniracetam and 3,475 about L-Theanine. Not medical advice.

Aniracetam
Supplement
L-Theanine
Supplement
Users say it helped60%helped405 reports · high confidence65%helped1,807 reports · high confidence
Verdict
Mostly positive
Mostly positive
ResearchBResearch: ModerateAResearch: Strong
Meta-analyses / RCTs1 / 918 / 78
Mainly used for
Anxiety
% reporting improvement
92% (191)91% (1289)
Focus
% reporting improvement
85% (200)88% (501)
Sleep
% reporting improvement
67% (12)78% (370)
Mood
% reporting improvement
87% (100)77% (223)
Energy
% reporting improvement
64% (22)68% (97)
Common side effectsdrowsiness, irritability, fatigue, headachedrowsiness, vivid dreams, fatigue, headache
Typical dose reported750 mg200 mg / bedtime
Aniracetam
Latest review conclusion

The most effective intervention for dementia available is symptomatic treatment for vascular dementia. Antipsychotic treatment for dementia alleviates cognitive dysfunction less effectively than does symptomatic treatment. Alternative therapies are also effective at present. Further research on causes and very early diagnosis of Alzheimer disease is warranted.

Psychopharmacology (Berl), 2018 ↗
What a user said
“Aniracetam: Anecdotally I could feel instantaneous mental improvement within 2-3 days... The most significant improvement was attention... organization, and confidence.”
Full Aniracetam profile →
L-Theanine
Latest review conclusion

This meta-analysis provides evidence that theanine plus caffeine, and theanine alone, could be beneficial for cognitive and mood outcomes. More research using tea beverages or tea-equivalent bioactive doses and research in free-living participants is needed.

Nutr Rev, 2025 ↗
What a user said
“This morning was my first time taking this combination along with my other daily vitamins and wow, what a difference it has made in my overall mood and anxiety!”
Full L-Theanine profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate