Conclusion: Current evidence suggests that creatine monohydrate supplementation may confer beneficial effects on cognitive function in adults, particularly in the domains of memory, attention time, and information processing speed. Larger robust clinical trials are warranted to further validate these findings. Furthermore, future research should investigate the influence of different populations and intervention durations on the effects of creatine monohydrate supplementation, as well as elucidate the precise mechanisms underlying its potential cognitive-enhancing properties.
PubMed 39070254 ↗Creatine Monohydrate
People mainly take Creatine Monohydrate for performance, energy, focus. Based on 139 first-hand reports and 23 meta-analyses & systematic reviews in the medical literature. Ranked #6 of 1,974 overall.
Of reports that state an outcome, 64% are positive.
What Creatine Monohydrate does, according to users
Of the people who reported each effect, the share who said it got better.
4 more with fewer than 3 reports
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Creatine supplementation enhanced measures of memory performance in healthy individuals, especially in older adults (66-76 years).
PubMed 35984306 ↗Conclusion: Creatine monohydrate supplementation was shown to be ineffective on endurance performance in a trained population.
PubMed 36877404 ↗Conclusion: Nor does the use of creatine supplementation increase the risk of total adverse outcomes, weight gain or renal and hepatic complications in females. However, all future studies of creatine supplementation in females should consider surveillance and comprehensive reporting of adverse outcomes to better inform participants and health professionals involved in future trials.
PubMed 32549301 ↗Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“Creatine and Protein powder (if you dont get sufficient amounts with your diet) are useful.”
“Creatine Monohydrate (~5g a day)”
“Creatine monohydrate 1 tsp”
“I've been taking 3,41 g creatine monohydrate (1 scoop) for a while now...I notice a difference, mainly that I have more energy during training sessions.”
“I've been using creative for literally 20 years...5-10 grams is plenty and all you need...5 grams was just as effective as 30 grams.”
Top discussions (5)
Other options for performance
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate