Possibly — but there are few reports. 79% of 19 people who reported on Tryptophan for mood say it improved. 11% noticed no change and 11% say it got worse.
“I personally respond to tryptophan better than 5HTP...I take 1000mg of tryptophan...3x a day before meals and it helps me immensely.”
“I took DLPA every morning and tryptophan every night...Did this for 6+ months and I cured my major depression accompanied w severe anhedonia.”
“With tryptophan I actually notice a more peaceful enjoyment of wakefulness, less anxiety and depression”
“I know tryptophan and carbohydrates help with this fatigue a little but tryptophan kills my appetite & sometimes motivation a little. After 2-3 days of taking tryptophan I usually start to feel anxious and obsessive”
Conclusion: The main areas of serotonin research provide no consistent evidence of there being an association between serotonin and depression, and no support for the hypothesis that depression is caused by lowered serotonin activity or concentrations. Some evidence was consistent with the possibility that long-term antidepressant use reduces serotonin concentration.
Conclusion: Reviewing these 11 RCTs, we concluded that taking 0.14-3 g of TRP per day in addition to the usual meal can be expected to improve the mood of healthy individuals. In order to estimate the optimum amount of TRP intake more accurately, further studies need to be conducted with more appropriate settings of intake period, intake frequency, and intake method.
Based on few reports — treat as anecdotal. Information only — not medical advice. How we count