Conclusion: Although the mechanism of action of the topical medicinal plant products provides a rationale basis for their use in the treatment of osteoarthritis, the quality and quantity of current research studies of effectiveness are insufficient. Arnica gel probably improves symptoms as effectively as a gel containing non-steroidal anti-inflammatory drug, but with no better (and possibly worse) adverse event profile. Comfrey extract gel probably improves pain, and Capsicum extract gel probably will not improve pain or function at the doses examined in this review. Further high quality, fully powered st
PubMed 23728701 ↗Stinging Nettle
People mainly take Stinging Nettle for hormones, libido. Based on 6 first-hand reports and 1 meta-analyses & systematic reviews in the medical literature. Ranked #1354 of 1,974 overall.
Of reports that state an outcome, 50% are positive.
What Stinging Nettle does, according to users
Of the people who reported each effect, the share who said it got better.
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“Stinging nettle has helped me.”
“Obviously SHBG is an issue, so I added stinging nettle and boron: Total: 743, SHBG 53, Free 69, Bioavailable, 146”
“Even then, it was unable to affect testosterone”
“My favorite libido boosters are Maca, Tribulus, Stinging Nettle, Ashwaghanda, and Fenugreek”
“I made a stack of tongkat Ali, tribulus, DAA, stinging nettle and ZMA”
Other options for hormones
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate