What are the side effects of Sarms?

Users most often report suppression, hair loss, terrible side, liver toxicity, heart attack. Side effects came up 16 times across 40 reports.

Sarms is not an approved supplement and carries serious risks. User reports can't establish safety. PubMed lists 3 meta-analyses and 2 randomized trials. Talk to a doctor or pharmacist, especially if you take other medication.

Sarms side effects

Across 40 first-hand reports, people mentioned a side effect 16 times (about 40 per 100 reports). The most common: suppression, hair loss, terrible side. User reports show what people notice — they can't tell you whether Sarms is safe for you.

High-risk compound. Not an approved supplement; serious and sometimes irreversible risks, banned in sport, may be restricted where you live.

Reported side effects

suppression8

hair loss2

terrible side1

liver toxicity1

heart attack1

acne1

hormonal disruption1

high cholesterol1

What got worse for some people

Hormones100% worse · 0% better · of 4

In their own words

“Sarms have changed my life... My libido definitely aint what it should be at times”

HelpedRead the discussion ↗

“I wouldn’t recommend taking sarms to fight depression and anxiety.”

Didn't helpRead the discussion ↗

“In my experience with SARMs causing hormone related acne, it usually normalizes and goes away over time.”

MixedRead the discussion ↗

“I would have skipped the SARMs and gone straight to roids... I did get hair loss and high cholesterol with SARMs though”

Didn't helpRead the discussion ↗

“I'm also on TRT + SARMs so I'm really fighting a losing battle more than likely”

Read the discussion ↗

Is Sarms safe? What the research covers

BResearch: Moderate3 meta-analyses · 2 randomized trials on PubMed

Sports Health · 2024

Performance-Enhancing Drugs in Healthy Athletes: An Umbrella Review of Systematic Reviews and Meta-analyses

Conclusion: In young healthy persons and athletes, creatine can safely provide a performance-enhancing benefit when taken in controlled doses. AAS, GH, and rHuEPO are associated with severe adverse events and do not support a performance benefit, despite showing the ability to change bodily composition, strength, and/or physiologic measures. Cannabis may have an ergolytic, instead of ergogenic, effect.

Clin Endocrinol (Oxf) · 2025

Selective Androgen Receptor Modulators (SARMs) Effects on Physical Performance: A Systematic Review of Randomized Control Trials

Conclusion: SARMs have a positive effect on physical performance and body composition and are associated with moderate rates of mild to moderate adverse effects (AEs) and a low rate of severe AEs.

Am J Sports Med · 2025

Athlete Selective Androgen Receptor Modulators Abuse: A Systematic Review

Conclusion: The results of this systematic review serve to educate sports medicine clinicians and researchers on how to better identify, diagnose, and treat athlete SARM abuse. SARM use is associated with increased muscle mass, hepatotoxicity, cardiotoxicity, tendon damage, and androgenic side effects throughout the body-including prostate enlargement and serum testosterone suppression. Identifying and treating SARM abuse requires taking a thorough substance and supplement use history with open communication, providing literature-supported patient education, negotiating SARM discontinuation, and performin