PlainPill
SupplementFocus

Pyritinol

People mainly take Pyritinol for focus. Based on 6 first-hand reports and 1 meta-analyses & systematic reviews in the medical literature. Ranked #1301 of 1,974 overall.

Compare with…Alternatives for focus
14
User score
Mostly negative
17% positive0% mixed17% negative67% unclear

Of reports that state an outcome, 50% are positive.

Clinical research
BModerate research base
1
meta-analyses
15
RCTs
126
papers

What Pyritinol does, according to users

Of the people who reported each effect, the share who said it got better.

Focus100% of 1
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

BModerate research base

At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.

Addiction · 2022 · Meta-analysis / systematic review
The efficacy and tolerability of pharmacologically active interventions for alcohol-induced hangover symptomatology: a systematic review of the evidence from randomised placebo-controlled trials

Conclusion: Only very low quality evidence of efficacy is available to recommend any pharmacologically active intervention for the treatment or prevention of alcohol-induced hangover. Of the limited interventions studied, all had favourable tolerability profiles and very low quality evidence suggests clove extract, tolfenamic acid and pyritinol may most warrant further study.

PubMed 34972259 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

200 mgdaily
400 mgas reported
600mgas reported

Reported side effects

How often each side effect came up across all reports.

seizures ×1mania ×1psychosis ×1nystagmus ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“We currently only offer Pramiracetam, Sulbutiamine, Piracetam, Aniracetam, Oxiracetam, Pyritinol, Picamilon, Choline Alpha GPC, Gingko Biloba, and Bacopa Monnieri.”
Source discussion ↗
“sulbutiamine and pyritinol 200mg”
Source discussion ↗
“he took his normal 400mg dose of pyritinol and went out for a mountain bike ride”
Source discussion ↗
Top discussions (3)

Other options for focus

Retatrutide
Peptide · 298 reports
73
100% report better focus
Mostly positiveBResearch: Moderate
Caffeine + L-Theanine
Supplement · 46 reports
72
91% report better focus
Mostly positive
Creatine Monohydrate
Supplement · 139 reports
66
94% report better focus
Mostly positiveAResearch: Strong
Semaglutide
Medication · 137 reports
65
67% report better focus
Mostly positiveAResearch: Strong
Intermittent Fasting
Lifestyle · 171 reports
63
94% report better focus
Mostly positive
Magnesium Glycinate
Supplement · 910 reports
63
70% report better focus
Mostly positiveCResearch: Limited

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate