PlainPill

Pea

People mainly take Pea for focus, energy, heart & lipids. Based on 11 first-hand reports and 90 meta-analyses & systematic reviews in the medical literature. Ranked #745 of 1,974 overall.

22
User score
Mostly positive
27% positive0% mixed0% negative73% unclear

Of reports that state an outcome, 100% are positive.

Clinical research
AStrong research base
90
meta-analyses
262
RCTs
20,893
papers

What Pea does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

Hum Reprod Update · 2024 · Meta-analysis / systematic review
Ultrasonographic criteria in the diagnosis of polycystic ovary syndrome: a systematic review and diagnostic meta-analysis

Conclusion: Subgroup analysis suggests the need to investigate any relative contributions of geographical differences on PCOS phenotypes. These findings may provide the basis for the development of strategies and best practices toward a standardized definition of PCOM and a more accurate ultrasonographic evaluation of PCOS.

PubMed 37804097 ↗
Nutrients · 2023 · Meta-analysis / systematic review
Palmitoylethanolamide in the Treatment of Chronic Pain: A Systematic Review and Meta-Analysis of Double-Blind Randomized Controlled Trials

Conclusion: The results of this systematic review and meta-analysis suggest that PEA is an effective and well-tolerated treatment for chronic pain. Further study is warranted to determine the optimal dosing and administration parameters of PEA for analgesic effects in the context of chronic pain.

PubMed 36986081 ↗
J Nutr · 2024 · Meta-analysis / systematic review
The Effect of Adding Protein to a Carbohydrate Meal on Postprandial Glucose and Insulin Responses: A Systematic Review and Meta-Analysis of Acute Controlled Feeding Trials

Conclusion: In people without diabetes, adding dairy or plant protein to a carbohydrate-containing meal elicits physiologically significant reductions in glucose AUC and increases insulin AUC. Animal protein may slightly reduce the glucose AUC and may increase the insulin AUC. In people with T2DM, protein may not have such large and consistent effects. Further research is needed to determine if the effects of protein differ by health status and protein source. This study was registered at PROSPERO as CRD42022322090.

PubMed 39019167 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

500 mgweekly or biweekly
micronizedas reported
as neededas reported

Reported side effects

How often each side effect came up across all reports.

increased blood ×1vasoconstriction ×1fast heartbeat ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“Try supplementing with PEA”
Source discussion ↗
“PEA (Phenylethylamine) - 500mg weekly or biweekly”
Source discussion ↗
“PEA most likely does a real number on your heart considering it increases blood pressure and causes vasoconstriction”
Source discussion ↗
“I plan to try various other things to alleviate this next time, i.e CDP Choline to upregulate dopamine receptors, Tyrosine/PEA and maybe grapefruit juice for metabolism reduction.”
Source discussion ↗
“Energy/PWO: + PEA”
Source discussion ↗
Top discussions (5)

Other options for focus

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate