Conclusion: We are not able to draw any conclusions regarding the relationship between intravenous synthetic oxytocin and postpartum depression based on current evidence due to the heterogeneity and small number of studies (n = 4). Considering limitations of the current literature and the current clinical prevalence of synthetic OT administration, we strongly recommend that rigorous studies examining the effects of synthetic OT exposure on PPD should be performed as well as continued work in defining the relationship between endogenous OT and PPD.
Does Oxytocin help with mood?
Possibly — but there are few reports. 100% of 10 people who reported on Oxytocin for mood say it improved. 0% noticed no change and 0% say it got worse.
High-risk compound. Not an approved supplement; serious risks and legal restrictions apply. Nothing here is a recommendation to use it.
Mood: what users report
100%better10 reports · few reports
10 better0 no change0 worse
What people say about Oxytocin and mood
“I added 100 mcg Oxytocin, in addition to the IPA, about a month ago... put on about ten pounds of muscle... helped with my social anxiety.”
“It does definitely seem to make me more calm and less impulsive/compulsive. So far not much of an increase in focus.”
“another one I have found that really helps in social settings is oxytocin”
“useful before social events, helped me be more convincing, increased intimacy and eagerness to connect with people. Effects only lasted a few hours.”
What the research says
AResearch: Strong611 meta-analyses · 1,989 trials on PubMed
Psychoneuroendocrinology · 2020
Oxytocin and postpartum depression: A systematic reviewSide effects people mention
headache 4flushing 1lactation 1downregulation 1head rush 1
What else is Oxytocin used for?
Based on few reports — treat as anecdotal. Information only — not medical advice. How we count