Niagen
People mainly take Niagen for energy, pain & inflammation. Based on 3 first-hand reports and 0 meta-analyses & systematic reviews in the medical literature. Ranked #1248 of 1,974 overall.
Of reports that state an outcome, 33% are positive.
What Niagen does, according to users
Of the people who reported each effect, the share who said it got better.
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
1–4 randomized controlled trials, no meta-analysis yet. The grade measures how much human research exists — read the conclusions below for what it found.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“after taking Niagen, I started to get tendonitis pretty regularly.”
“Ditch the Niagen and replace it Niacinamide or just Niacin.”
“Tru niagen helps me power through my day. Gets rid of the heavy tired feeling”
Top discussions (3)
Other options for energy
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate