Cancer Chemother Pharmacol · 2024
Predictive performance of population pharmacokinetic models of imatinib in chronic myeloid leukemia patientsConclusion: Menon et al. model was able to predict well for our clinical data where it had the relative mean prediction error percentage ≤ 20%, relative median absolute prediction error ≤ 30% and relative root mean square error close to zero. Based on this final model, we proposed a dosing nomogram for various weight groups, which could potentially help to maintain the trough concentrations in the therapeutic range.