J Affect Disord · 2022
Augmentation strategies for treatment resistant major depression: A systematic review and network meta-analysisDoes Lisdexamfetamine help with mood?
For some people. 50% of 82 people who reported on Lisdexamfetamine for mood say it improved. 5% noticed no change and 45% say it got worse. That is below the typical result for mood (84% across 108 options).
Mood: what users report
50%better82 reports · medium confidence
41 better4 no change37 worse
Ranked #97 of 108 for mood.
What people say about Lisdexamfetamine and mood
“I got diagnosed with ADHD and tried Ritalin and Elvanse and they do help somewhat when I need to learn for an exam but I hate the feeling of being on them.”
“I used vyvanse daily for years. I have not felt pleasure, motivation, or desire in the same way since.”
“Concerta, Vyvanse (they gave me stimulation and a mood booster but it felt really artificial, left me with more depression when I was not taking it)”
“now, even after taking 7-10 days off it seems that 60mg still is just OK and i still cant reduce the dose successfully and feel slow/down unless i bump up to even more than 60mg.”
What the research says
AResearch: Strong58 meta-analyses · 112 trials on PubMed
Side effects people mention
anxiety 23insomnia 14fatigue 10irritability 9tolerance 7
What else is Lisdexamfetamine used for?
Information only — not medical advice. How we count