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EPA side effects

Across 41 first-hand reports, people mentioned a side effect 7 times (about 17 per 100 reports). The most common: dizziness, insomnia, jitteriness. User reports show what people notice — they can't tell you whether EPA is safe for you.

Reported side effects

dizziness2
insomnia1
jitteriness1
irritability1
decreased appetite1
joint pain1

In their own words

“I've tried EPA on two separate occasions... I noticed myself feeling more stimulated, irritable, but also a bit moodier and low. When I stopped taking EPA, I felt better”
MixedRead the discussion ↗
“Two weeks in and I see a significant improvement in cognition and memory...vision has *slightly* improved”
HelpedRead the discussion ↗

Is EPA safe? What the research covers

AResearch: Strong559 meta-analyses · 1,301 randomized trials on PubMed
Cochrane Database Syst Rev · 2024
Nutritional interventions for preventing and treating pressure ulcers

Conclusion: The benefits of nutritional interventions with various compositions for pressure ulcer prevention and treatment are uncertain. There may be little or no difference compared to standard nutrition or placebo. Nutritional supplements may not increase gastrointestinal side effects, but the evidence is very uncertain. Larger studies with similar nutrient compositions would reduce these uncertainties. No study investigated the effects of special diets (e.g. protein-enriched diet, vegetarian diet) on pressure ulcer incidence and healing.

EPA side effects: what 41 users report — PlainPill