Duloxetine reviews: what real users say
We read 45 first-hand mentions of Duloxetine from health and supplement communities. 31 of them say clearly how it went — and 42% of those say it helped.
Where people say it works: energy (71% of 7), anxiety (80% of 5).
Most common complaints: fatigue, withdrawal, emotional blunting, brain fog, emotional instability. All side effects →
Positive experiences
“Ultimately I switched to Cymbalta + wellbutrin... about 25% better than a straight ssri.”
“I started taking Cymbalta for it ... it seemed to really help the anxiety, and I could drink coffee again”
“Ive been on Cymbalta for about 7 months now and I feel about 80% better. I don't have panic attacks anymore”
“This was SIGNIFICANTLY improvement for me. Cognition was better, weight gain was less, and libido was much improved”
“Cymbalta is helping me cope better in social anxiety situations as soon as 2 weeks of taking it which is great imo”
“Cymbalta helped as well but I was too nauseous with it.”
Negative and mixed experiences
“Cymbalta here. Absolutely ruined my life. Started early 2018 and quit cold turkey (nobody told me I couldn't) later that same year. I'm still a mess all this time later.”
“I also weaned off of duloxetine because it quit working for the pain and made me depressed non-motivated.”
“Duloxetine's potent NRI increased my drive, energy and mood but it wasn't effective enough at 60mg.”
“I hated Cymbalta when I took it. I know the feeling you describe of zombification.”
“doctors prescribe stuff like cymbalta/lexapro (both of which I have been on and had bad side effects and even worse withdrawal symptoms)”
“Duloxetine helped push me to act but increased baseline hyperarousal”
Quotes are verbatim and link to the original public discussion. Information only — not medical advice. How we collect reports