PlainPill

Clomid

People mainly take Clomid for hormones, mood, focus. Based on 36 first-hand reports and 3 meta-analyses & systematic reviews in the medical literature. Ranked #436 of 1,974 overall.

28
User score
Mostly positive
19% positive6% mixed6% negative69% unclear

Of reports that state an outcome, 61% are positive.

Clinical research
BModerate research base
3
meta-analyses
5
RCTs
196
papers

What Clomid does, according to users

Of the people who reported each effect, the share who said it got better.

3 more with fewer than 3 reports
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

BModerate research base

At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.

Hum Fertil (Camb) · 2022 · Meta-analysis / systematic review
Multiple pregnancy rate in patients undergoing treatment with clomifene citrate for WHO group II ovulatory disorders: a systematic review

Conclusion: This review suggests that contemporary single agent clomifene use following current guidelines in terms of indication, results in a lower than expected multiple pregnancy rate. Further evidence from clinical practice is required to ensure that patients are adequately informed.

PubMed 33451262 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

50 mg maximumas reported
EOD for 2 monthsas reported
25 mgdaily
12.5mgEOD
12.5 mgdaily
40/40/20/20as reported

Reported side effects

How often each side effect came up across all reports.

optic nerve ×1liver damage ×1aggression ×1emotional instability ×1brain fog ×1mood swings ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“I'd add clomid, peptides and nad”
Source discussion ↗
“If you want to actually boost your testosterone, look into Clomid, HCG and HMG.”
Source discussion ↗
“If you want a pill to significantly boost those markers, nothing is going to compare to clomid.”
Source discussion ↗
“Will certainly boos your T levels...High does of clomid will cause you to become incredibly aggressive and emotional”
Source discussion ↗
“Tianeptine has been miraculous in curing my temporary Clomid induced depression.”
Source discussion ↗
Top discussions (5)

Other options for hormones

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate