PlainPill

Cetirizine

Based on 7 first-hand reports and 45 meta-analyses & systematic reviews in the medical literature. Ranked #857 of 1,974 overall.

19
User score
Mixed
29% positive43% mixed0% negative29% unclear

Of reports that state an outcome, 40% are positive.

Clinical research
AStrong research base
45
meta-analyses
400
RCTs
1,898
papers

What Cetirizine does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

J Eur Acad Dermatol Venereol · 2024 · Meta-analysis / systematic review
Treatment of acute urticaria: A systematic review

Conclusion: The addition of corticosteroids to an antihistamine as treatment for AU needs to be further investigated. Well-designed, high-quality interventional trials are needed to establish evidence-based treatment guidelines for AU.

PubMed 38420865 ↗
J Asthma · 2025 · Meta-analysis / systematic review
Efficacy and safety of montelukast-levocetirizine combination therapy in combined allergic rhinitis and asthma syndrome: a systematic review and meta-analysis

Conclusion: In summary, this meta-analysis demonstrated the efficacy of montelukast combined with levocetirizine in the treatment of nasal symptoms in AR with asthma, indicating that the combination of montelukast with levocetirizine is more effective in improving symptoms of allergic rhinitis than monotherapy and has good safety.

PubMed 39394937 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

dailyas reported
10 mgas reported
20 mgdaily
5 mgonly when really needed
10 mgtwice daily

Reported side effects

How often each side effect came up across all reports.

drowsiness ×2fatigue ×1itching ×1withdrawal ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

More medications

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate