Polygala vs Polygala Tenuifolia for mood
Short answer: For mood, more users report improvement with Polygala Tenuifolia — 100% of 19 reports, versus 89% of 53 for Polygala.
Polygala has 6 meta-analyses and 3 randomized trials on PubMed; Polygala Tenuifolia has 5 and 3.
Based on 247 reports about Polygala and 80 about Polygala Tenuifolia. Not medical advice.
| Polygala Supplement | Polygala Tenuifolia Supplement | |
|---|---|---|
| Users say it helped | 64%helped96 reports · medium confidence | 86%helped28 reports · medium confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | BResearch: Moderate | BResearch: Moderate |
| Meta-analyses / RCTs | 6 / 3 | 5 / 3 |
| Mainly used for | ||
| Mood % reporting improvement | 89% (53) | 100% (19) |
| Focus % reporting improvement | 90% (29) | 91% (11) |
| Anxiety % reporting improvement | 88% (32) | 60% (5) |
| Energy % reporting improvement | 92% (13) | 100% (4) |
| Memory % reporting improvement | 86% (7) | — |
| Common side effects | antisocial, changed heart, mania, sleep cycle | stomach issues, flatulence, anxiety, drowsiness |
| Typical dose reported | 100 mg / 3x daily | 100-300 mg / 3x daily or variable |
This review on traditional uses and phytopharmacological potential of the genus Polygala revealed updated insights which can be explored for further mechanism-based pharmacological activities and structure/activity relationships studies and a better comprehension of the development of Chinese medicine preparations. However some pharmacological studies showed several gaps such as incomplete methodologies and ambiguous findings. More high scientific quality preclinical studies with pharmacokinetic considerations will be required in the future to assess the traditional uses of some species of thi
J Ethnopharmacol, 2020 ↗“I also take 100mg of Polygala 3x a day sublingual. It helps with recurring bad thoughts, and focus...helps with overall mood and sleep.”
We encountered Acoris gramineus rhizome (AGR), Panax ginseng, Polygala tenuifolia and Poria cocos as the four most frequently used herbs as single/herbal mixtures that were associated with positive cognitive enhancing outcomes. This review focuses on the evidence of their medicinal effects attributed to those constituents present in relatively high concentration.
Mini Rev Med Chem, 2012 ↗“150mg had immediate antidepressant effects for me. It's worked great for mood and focus...It has improved my depression, anhedonia, and ADHD all at once.”
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate