PlainPill

Cistanche vs Fadogia Agrestis for hormones

Short answer: For hormones, users rate them about the same: 82% report improvement with Cistanche (40 reports) and 82% with Fadogia Agrestis (17 reports).

Cistanche has 4 meta-analyses and 6 randomized trials on PubMed; Fadogia Agrestis has 0 and 0.

Based on 321 reports about Cistanche and 104 about Fadogia Agrestis. Not medical advice.

Cistanche
Supplement
Fadogia Agrestis
Supplement
Users say it helped66%helped132 reports · high confidence43%helped36 reports · medium confidence
Verdict
Mostly positive
Mixed
ResearchBResearch: ModerateDResearch: None
Meta-analyses / RCTs4 / 60 / 0
Mainly used for
Libido
% reporting improvement
80% (51)91% (11)
Hormones
% reporting improvement
82% (40)82% (17)
Mood
% reporting improvement
73% (41)100% (2)
Energy
% reporting improvement
67% (30)50% (2)
Anxiety
% reporting improvement
88% (25)—
Common side effectsfatigue, anhedonia, drowsiness, hair lossliver toxicity, toxicity, kidney toxicity, testicular toxicity
Typical dose reported210 mg / daily425 mg / daily
Cistanche
Latest review conclusion

Dietary supplements have a positive impact on hair density, terminal hair density, and blind doctor evaluations in patients with androgenetic alopecia, with good tolerability. They may serve as beneficial adjuncts or alternatives to conventional treatments. Future large-scale, high-quality RCTs are needed to verify these findings.

Front Nutr, 2025 ↗
What a user said
“Cistanche extract increases my drive, energy and vigor. It makes me want to attack life. I get better sleep...My work ethic has improved. My memory. my attitude towards life. Every facet of my life has been altered in a positive meaningful way.”
Full Cistanche profile →
Fadogia Agrestis
What a user said
“I think tongkat ali and cistanche/fadogia were a game changer for me”
Full Fadogia Agrestis profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate