Cagrilintide vs NAC for appetite
Short answer: For appetite, more users report improvement with Cagrilintide — 100% of 8 reports, versus 91% of 34 for NAC.
Cagrilintide has 9 meta-analyses and 15 randomized trials on PubMed; NAC has 387 and 767.
Based on 32 reports about Cagrilintide and 2,058 about NAC. Not medical advice.
| Cagrilintide Peptide | NAC Supplement | |
|---|---|---|
| Users say it helped | 82%helped11 reports · few reports | 54%helped947 reports · high confidence |
| Verdict | Mostly positive | Mixed |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 9 / 15 | 387 / 767 |
| Mainly used for | ||
| Mood % reporting improvement | — | 65% (323) |
| Anxiety % reporting improvement | — | 90% (301) |
| Focus % reporting improvement | — | 81% (170) |
| Energy % reporting improvement | — | 73% (91) |
| Sleep % reporting improvement | — | 71% (48) |
| Common side effects | fatigue, appetite loss, depressive episode | anhedonia, stomach issues, depression, emotional blunting |
| Typical dose reported | Not listed | 600 mg |
GLP-1RAs are efficacious in treating adults with type 2 diabetes. Compared with the placebo, tirzepatide was the most effective GLP-1RA drug for glycaemic control by reducing haemoglobin A1c and fasting plasma glucose concentrations. GLP-1RAs also significantly improved weight management for type 2 diabetes, with CagriSema performing the best for weight loss. The results prompt safety concerns for GLP-1RAs, especially with high dose administration, regarding gastrointestinal adverse events.
BMJ, 2024 ↗“Cagri was a game changer for me. I added 1mg and thats been more than enough.”
Taken together, these preliminary findings suggest that dietetic approaches might be included as part of BD treatment. Also considering the high risk of metabolic disorders in individuals with BD, they should be encouraged to choose healthy dietary lifestyles, including daily intake of fruits, vegetables, seafood and whole grains.
Nutr Neurosci, 2023 ↗“NAC has helped me stay calm and reduce anxiety as well as gives me loads of energy if I am sleep deprived.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate