PlainPill

Vitamin D3 with K2

People mainly take Vitamin D3 with K2 for mood, energy. Based on 11 first-hand reports. Ranked #256 of 1,974 overall.

38
User score
Mostly positive
64% positive0% mixed0% negative36% unclear

Of reports that state an outcome, 100% are positive.

Clinical research
Research pending

What Vitamin D3 with K2 does, according to users

Of the people who reported each effect, the share who said it got better.

1 more with fewer than 3 reports
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

Research data for Vitamin D3 with K2 is being compiled.

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

5000 IU75% of days
100,000 IU D3 with 45 mg K2daily
dailyas reported
5000 IUdaily

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“I do use Yerba Mate, Creatine, ALCAR, Fish Oil, D3 w/ K2 and Coffee of course... but those are more subtle.”
Source discussion ↗
“If I don't take them, depression creeps up without even noticing.”
Source discussion ↗
“D and K2 for proper calcium absorption.”
Source discussion ↗
“If you take K2 along with D3 you negate the build up of free-floating calcium which is the only known danger to high dose D3. I am living proof that daily supplementation of 100,000IU of D3 with 45mg of K2 is not only sa”
Source discussion ↗
“Swap your D3 for D3+K2”
Source discussion ↗
Top discussions (5)

Other options for mood

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate