PlainPill
SupplementMoodPain & inflammation

Turmeric Curcumin

People mainly take Turmeric Curcumin for mood, pain & inflammation. Based on 8 first-hand reports and 22 meta-analyses & systematic reviews in the medical literature. Ranked #1395 of 1,974 overall.

Compare with…Alternatives for mood
14
User score
Mixed
12% positive12% mixed0% negative75% unclear

Of reports that state an outcome, 50% are positive.

Clinical research
BModerate research base
22
meta-analyses
3
RCTs
112
papers

What Turmeric Curcumin does, according to users

Of the people who reported each effect, the share who said it got better.

Mood100% of 2Pain & inflammation100% of 1
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

BModerate research base

At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.

Cytokine · 2023 · Meta-analysis / systematic review
Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults: A GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials

Conclusion: Also, turmeric/curcumin supplementation significantly improved anti-oxidant activity through enhancing TAC (WMD = 0.21 mmol/l; 95 % CI: 0.08, 0.33), reducing MDA levels (WMD = -0.33 µmol /l; 95 % CI: -0.53, -0.12), and SOD activity (WMD = 20.51 u/l; 95 % CI: 7.35, 33.67). It seems that turmeric/curcumin supplementation might be used as a viable intervention for improving inflammatory/oxidative status of individuals.

PubMed 36804260 ↗
J Med Food · 2016 · Meta-analysis / systematic review
Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Conclusion: However, the total number of RCTs included in the analysis, the total sample size, and the methodological quality of the primary studies were not sufficient to draw definitive conclusions. Thus, more rigorous and larger studies are needed to confirm the therapeutic efficacy of turmeric for arthritis.

PubMed 27533649 ↗
Nutrients · 2024 · Meta-analysis / systematic review
Curcumin Attenuates Hyperglycemia and Inflammation in Type 2 Diabetes Mellitus: Quantitative Analysis of Randomized Controlled Trial

Conclusion: The findings observed in this study suggest that curcumin can ameliorate hyperglycemia and inflammation in T2D compared to a placebo. While the potential benefits were observed, it is recommended that future trials focus on finding a suitable dose and duration of intervention and incorporate formulation in curcumin to enhance its absorption.

PubMed 39683570 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

500 mg2x daily (inconsistent)
500 mgdaily

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“Turmeric & Curcumin, Gannoderma”
Source discussion ↗
“If this wasn't from heavy metal contamination, the turmeric may have been your problem here. It elevates liver enzymes.”
Source discussion ↗
“I take turmeric pretty much every day (Just one caplet) and it has helped keep my arthritis flair ups from getting too painful.”
Source discussion ↗
“Vitamin C and Turmeric/Curcumin: inflammation has been associated with depression, so the turmeric is to support that.”
Source discussion ↗
“turmeric/curcumin, which is quite on trend but also genuinely seems to be a good anti-inflammatory”
Source discussion ↗
Top discussions (5)

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User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate