5
User score
Not enough data0% positive0% mixed0% negative100% unclear
Of reports that state an outcome, 0% are positive.
Clinical research
Research pending
What Tobacco does, according to users
Of the people who reported each effect, the share who said it got better.
No specific effects reported yet.
betterno changeworse
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
Research data for Tobacco is being compiled.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
No doses stated in the reports so far.
Reported side effects
How often each side effect came up across all reports.
No side effects reported so far.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“Tobacco has a much more potent effect in this manner due to the MAOIs”
“These compounds are probably the reason that coffee and tobacco are associated with lower risk of (non-vascular) dementia. That being said they're also MAOIs so you might want to be careful with them.”
More substances
Yerba Mate
Substance · 57 reports
100% report better energy
Mostly positiveAResearch: Strong
Ephedrine
Substance · 44 reports
100% report better energy
MixedAResearch: Strong
Coffee
Substance · 156 reports
88% report better energy
Mixed
LSD
Substance · 62 reports
84% report better mood
MixedAResearch: Strong
Caffeine
Substance · 761 reports
83% report better energy
MixedAResearch: Strong
Kratom
Substance · 194 reports
87% report better mood
MixedBResearch: Moderate
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate