PlainPill

Thiamin

People mainly take Thiamin for anxiety, mood. Based on 3 first-hand reports and 31 meta-analyses & systematic reviews in the medical literature. Ranked #1372 of 1,974 overall.

14
User score
Mostly positive
33% positive0% mixed0% negative67% unclear

Of reports that state an outcome, 100% are positive.

Clinical research
AStrong research base
31
meta-analyses
73
RCTs
3,196
papers

What Thiamin does, according to users

Of the people who reported each effect, the share who said it got better.

betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

Clin Nutr · 2022 · Meta-analysis / systematic review
ESPEN micronutrient guideline

Conclusion: This guideline should enable addressing suboptimal and deficient status of a bundle of MNs in at-risk diseases. In particular, it offers practical advice on MN provision and monitoring during nutritional support.

PubMed 35365361 ↗
Obes Surg · 2019 · Meta-analysis / systematic review
The Effect of Bariatric Surgery on Peripheral Polyneuropathy: a Systematic Review and Meta-analysis

Conclusion: In subgroup of patients with follow-up of more than 6 months after surgery, a significant reduction in NDS was detected while this reduction was not significant in patients with a follow-up of 6 months or less. Bariatric surgery had a positive effect on peripheral neuropathy, though many studies showed neuropathy as one of the complications of bariatric surgery.

PubMed 31256355 ↗
Cochrane Database Syst Rev · 2001 · Meta-analysis / systematic review
Thiamine for Alzheimer's disease

Conclusion: It is not possible to draw any conclusions from this review. The number of people included in the studies if less than 50 and the reported results are inadequate.

PubMed 11405995 ↗
Br J Nutr · 2009 · Meta-analysis / systematic review
Dietary assessment methods for micronutrient intake in infants, children and adolescents: a systematic review

Conclusion: Using serum levels of micronutrient demonstrated that the 3 d weighed dietary records was superior to the FFQ as a tool to validate micronutrient intakes. Including supplement users generally improved the correlations between micronutrient intakes estimated by any of the dietary intake methods and respective biochemical indices.

PubMed 20100370 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

occasionalas reported

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“Be sure to get Thiamin since drinking alcohol”
Source discussion ↗
“I keep Niacin and Thiamin around for occasional usage, very occasional.”
Source discussion ↗
“Thiamin is so underated, it was a lifechanger for me.”
Source discussion ↗
Top discussions (3)

Other options for anxiety

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate