People mainly take Testosterone (trt) for mood, libido, weight loss. Based on 3 first-hand reports and 50 meta-analyses & systematic reviews in the medical literature. Ranked #756 of 1,974 overall.
Of reports that state an outcome, 100% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: However, it should be recognized that the number of studies on benefits of T supplementation is too limited to draw final conclusions. Longer and larger studies are needed to better clarify the role of TRT in such chronic conditions.
PubMed 24054931 ↗Conclusion: Intramuscular TRT is more effective than transdermal formulations at increasing LBM and improving muscle strength in middle-aged and older men, particularly in the lower extremities.
PubMed 29542875 ↗Conclusion: Gonadotropin therapy, even with urinary derivatives, is a suitable option in inducing/restoring fertility in azoospermic HHG subjects. Gonadotropins appear to be more efficacious in subjects with a pure secondary nature (low gonadotropins) and a post-pubertal onset of the disorder, whereas previous TRT does not affect outcome.
PubMed 25271205 ↗Conclusion: Also, further research is required before definitive conclusions on efficacy and safety can be made. This systematic review was registered at PROSPERO as CRD42020173623.
PubMed 33150931 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“I'm 45 and I'm on 200 a week from my doctor. I rarely lift as I have had 5 back surgeries and I take it for the sexual, mental and overall health benefits”
“Started TRT 3 years ago, worked out inconsistently for years and lost some weight but never the results I wanted”
“Obviously the biggest difference here is hitting steps and nutritional targets”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate