PlainPill

Tesamorelin/Ipamorelin

People mainly take Tesamorelin/Ipamorelin for weight loss, sleep. Based on 6 first-hand reports. Ranked #560 of 1,974 overall.

25
User score
Mostly positive
50% positive17% mixed0% negative33% unclear

Of reports that state an outcome, 75% are positive.

Clinical research
Research pending
High-risk compound. Peptides are not approved as supplements, carry serious and sometimes irreversible risks, are banned in competitive sport and may be restricted where you live. Nothing here is a recommendation to use it.

What Tesamorelin/Ipamorelin does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

Research data for Tesamorelin/Ipamorelin is being compiled.

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

2 mg/100 mcg1x per day
TESA 2mgIPA 300 mcg

Reported side effects

How often each side effect came up across all reports.

water retention ×1aching joints ×1increased heart ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“They put me on tesamorelin/ipamorelin. The next lab everything for the liver was back out of the red.”
Source discussion ↗
“I have been doing tesa/ipa 2mg/100mcg 1x per day with ipa/cjc 100mcg 2x per day with alternate day fasting. Im shredding fat. Probably cause of the fasting but Ive preserved muscle and strength”
Source discussion ↗
“MOTS-C, NAD+, Tesa & Ipa”
Source discussion ↗
Top discussions (3)

Other options for weight loss

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate