5
User score
Not enough data0% positive0% mixed0% negative100% unclear
Of reports that state an outcome, 0% are positive.
Clinical research
Research pending
High-risk compound. SARMs are not approved as supplements, carry serious and sometimes irreversible risks, are banned in competitive sport and may be restricted where you live. Nothing here is a recommendation to use it.
What S-4 (andarine) does, according to users
Of the people who reported each effect, the share who said it got better.
No specific effects reported yet.
betterno changeworse
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
Research data for S-4 (andarine) is being compiled.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
25 mgas reported
Reported side effects
How often each side effect came up across all reports.
No side effects reported so far.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“I ordered their S-4: 25 mg GW501516: 10 mg stack.”
“S-4 and Andarine (winnyvar), RAD-140 (testolone/ragebolone), and S-23 (sarmbolone).”
More sarms
LGD-4033
SARM · 125 reports
98% report better performance
MixedBResearch: Moderate
GW-501516
SARM · 67 reports
100% report better weight loss
Mostly positiveDResearch: None
MK-677
SARM · 168 reports
81% report better sleep
MixedBResearch: Moderate
RAD-140
SARM · 181 reports
96% report better performance
MixedDResearch: None
MK-2866
SARM · 158 reports
90% report better performance
MixedDResearch: None
AC-262
SARM · 8 reports
100% report better performance
Mostly positive
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate