PlainPill

Pirlindole

People mainly take Pirlindole for mood, focus. Based on 2 first-hand reports. Ranked #1873 of 1,974 overall.

5
User score
Mostly negative
0% positive50% mixed50% negative0% unclear

Of reports that state an outcome, 0% are positive.

Clinical research
Research pending

What Pirlindole does, according to users

Of the people who reported each effect, the share who said it got better.

betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

Research data for Pirlindole is being compiled.

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

1.5 weeksas reported
25 mgspecific days, never 3 days in a row

Reported side effects

How often each side effect came up across all reports.

insomnia ×1heart palpitations ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“did it actually seem to make my depression worse after several days...my cognition was negatively impacted...Sleep and mood improved the first three days...before it fell off a cliff.”
Source discussion ↗
“A pharmaceutical reversible MAO-I that feels VERY nice, but can cause severe insomnia and annoying ass heart palpitations.”
Source discussion ↗
Top discussions (2)

Other options for mood

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate