World Neurosurg · 2021
A Systematic Review and Meta-Analysis of Antiepileptic Prophylaxis in Spontaneous Intracerebral HemorrhageConclusion: This systematic review and meta-analysis including recent studies focusing on newer AEDs supports the 2015 guidelines regarding AED use in spontaneous ICH. There are some important caveats, including a possible confounding association between AED use and higher ICH score and the overall poor quality of the available data. A randomized clinical trial may be helpful.