PlainPill

Mushrooms

People mainly take Mushrooms for memory, mood. Based on 9 first-hand reports and 49 meta-analyses & systematic reviews in the medical literature. Ranked #952 of 1,974 overall.

15
User score
Mixed
11% positive11% mixed11% negative67% unclear

Of reports that state an outcome, 33% are positive.

Clinical research
AStrong research base
49
meta-analyses
49
RCTs
8,843
papers

What Mushrooms does, according to users

Of the people who reported each effect, the share who said it got better.

betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

Cochrane Database Syst Rev · 2024 · Meta-analysis / systematic review
Psychedelic-assisted therapy for treating anxiety, depression, and existential distress in people with life-threatening diseases

Conclusion: Implications for practice Psychedelic-assisted therapy with classical psychedelics (psilocybin, LSD) may be effective for treating anxiety, depression, and possibly existential distress, in people facing a life-threatening disease. Psychedelic-assisted therapy seemed to be well tolerated, with no treatment-emergent serious adverse events reported in the studies included in this review. However, the certainty of evidence is low to very low, which means that we cannot be sure about these results, and they might be changed by future research. At the time of this review (2024), psychedelic drugs a

PubMed 39260823 ↗
Adv Nutr · 2024 · Meta-analysis / systematic review
Comparison of the Effect of Daily Vitamin D2 and Vitamin D3 Supplementation on Serum 25-Hydroxyvitamin D Concentration (Total 25(OH)D, 25(OH)D2, and 25(OH)D3) and Importance of Body Mass Index: A Systematic Review and Meta-Analysis

Conclusion: Vitamin D3 leads to a greater increase of 25(OH)D than vitamin D2, even if limited to daily dose studies, but vitamin D2 and vitamin D3 had similar positive impacts on their corresponding 25(OH)D hydroxylated forms. Next to baseline 25(OH)D concentration, BMI should be considered when comparing the effect of daily vitamin D2 and vitamin D3 supplementation on total 25(OH)D concentration. This study was registered in PROSPERO as CRD42021272674.

PubMed 37865222 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

dailyas reported
2 gas reported

Reported side effects

How often each side effect came up across all reports.

psychosis ×1social withdrawal ×1fatigue ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“I have found that shrooms are more than likely what exacerbated my symptoms.”
Source discussion ↗
“I would recommend mushrooms. 🍄”
Source discussion ↗
“higher mushroom consumption tracked with slower cognitive decline in older adults”
Source discussion ↗
“a calcium complex with Vit K and Magnesium, b-complex, krill oil (like you), zinc, and a green powder, mushrooms (non hallucenogenic) and collagen every day”
Source discussion ↗
“I did mushrooms for the first time about a week ago. 2 grams only. I felt weird and giggly for several hours, but certainly nothing like a breakthrough... I felt pretty good the next day but tired. Didn't feel like it ch”
Source discussion ↗
Top discussions (5)

Other options for memory

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate