Conclusion: Implications for practice Psychedelic-assisted therapy with classical psychedelics (psilocybin, LSD) may be effective for treating anxiety, depression, and possibly existential distress, in people facing a life-threatening disease. Psychedelic-assisted therapy seemed to be well tolerated, with no treatment-emergent serious adverse events reported in the studies included in this review. However, the certainty of evidence is low to very low, which means that we cannot be sure about these results, and they might be changed by future research. At the time of this review (2024), psychedelic drugs a
PubMed 39260823 ↗Mushrooms
People mainly take Mushrooms for memory, mood. Based on 9 first-hand reports and 49 meta-analyses & systematic reviews in the medical literature. Ranked #952 of 1,974 overall.
Of reports that state an outcome, 33% are positive.
What Mushrooms does, according to users
Of the people who reported each effect, the share who said it got better.
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Nevertheless, the evidence is inconclusive to recommend the routine use of mushrooms for cancer patients. More trials are needed to explore mushroom use during and after cancer treatment.
PubMed 36995535 ↗Conclusion: Although commonly unreported, potential side effects of HE include stomach discomfort, headache, and allergic reactions. https://www.crd.york.ac.uk/PROSPERO/view/CRD42024571250.
PubMed 40959699 ↗Conclusion: Vitamin D3 leads to a greater increase of 25(OH)D than vitamin D2, even if limited to daily dose studies, but vitamin D2 and vitamin D3 had similar positive impacts on their corresponding 25(OH)D hydroxylated forms. Next to baseline 25(OH)D concentration, BMI should be considered when comparing the effect of daily vitamin D2 and vitamin D3 supplementation on total 25(OH)D concentration. This study was registered in PROSPERO as CRD42021272674.
PubMed 37865222 ↗Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“I have found that shrooms are more than likely what exacerbated my symptoms.”
“I would recommend mushrooms. 🍄”
“higher mushroom consumption tracked with slower cognitive decline in older adults”
“a calcium complex with Vit K and Magnesium, b-complex, krill oil (like you), zinc, and a green powder, mushrooms (non hallucenogenic) and collagen every day”
“I did mushrooms for the first time about a week ago. 2 grams only. I felt weird and giggly for several hours, but certainly nothing like a breakthrough... I felt pretty good the next day but tired. Didn't feel like it ch”
Top discussions (5)
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- LSD (normal and microdosing) is by far the best nootropic ↗
Other options for memory
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate