Based on 6 first-hand reports and 157 meta-analyses & systematic reviews in the medical literature. Ranked #1464 of 1,974 overall.
Of reports that state an outcome, 0% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: This guideline should enable addressing suboptimal and deficient status of a bundle of MNs in at-risk diseases. In particular, it offers practical advice on MN provision and monitoring during nutritional support.
PubMed 35365361 ↗Conclusion: Deficiencies or imbalances in specific vitamins and minerals, especially vitamin B, vitamin D, Fe, Se, and Zn are involved in the pathogenesis of AGA and may represent modifiable risk factors for the treatment and prevention of this condition.
PubMed 39440586 ↗Conclusion: This review sheds light on specific promising areas of research that require further study, including the need for interventional studies evaluating serum zinc, vitamin D, and vitamin E supplementation for seborrheic dermatitis. The negative consequences of a Western diet, alcohol use, obesity, and the benefits of fruit consumption are well known; however, to fully understand their specific relationships to seborrheic dermatitis, further cohort or interventional studies are needed.
PubMed 39102684 ↗Conclusion: Untested chemicals should not be presumed to be safe to brain development, and chemicals in existing use and all new chemicals must therefore be tested for developmental neurotoxicity. To coordinate these efforts and to accelerate translation of science into prevention, we propose the urgent formation of a new international clearinghouse.
PubMed 24556010 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“taking histamine-increasing supplements like Zinc, L-Histidine, Manganese, Nicotinic Acid and Vitamin C.”
“The RDA of ~2mg was decided based on the amount of manganese present in the diets of healthy subjects.”
“Manganese is a cofactor in a lot of things in the body, apparently one of those things is thyroxine”
“I've tried taking L-Tyrosine, Zinc Picolinate, L-Glutamine, L-Threonate, Selenium, Manganese, Magnesium Glycinate”
“Manganese is helps Copper be absorbed.”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate