People mainly take Magnesium Chloride for anxiety, mood. Based on 18 first-hand reports and 16 meta-analyses & systematic reviews in the medical literature. Ranked #213 of 1,974 overall.
Of reports that state an outcome, 82% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Balanced electrolyte solutions are associated with less hyperchloraemic metabolic acidosis compared to normal saline, however it remains uncertain whether lower-chloride solutions lead to improved graft outcomes compared to normal saline.
PubMed 27502170 ↗Conclusion: The SCI community is encouraged by the progression of novel therapies from "bench to bedside" and the initiation of clinical trials for a number of different treatments. The task of clinical evaluation, however, is substantial, and many years will be required before the actual efficacy of the treatments currently in evaluation will be determined.
PubMed 20881470 ↗Conclusion: There is not enough evidence to show any difference between magnesium maintenance therapy compared with either placebo or no treatment, or alternative therapies (ritodrine or terbutaline) in preventing preterm birth after an episode of threatened preterm labour.
PubMed 23728634 ↗Conclusion: There is not enough evidence to show any difference between magnesium maintenance therapy compared with either placebo or no treatment, or alternative therapies (ritodrine or terbutaline) in preventing preterm birth after an episode of threatened preterm labour.
PubMed 20614423 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“Another good form is Magnesium Chloride. You can spray it on your biceps, chest, etc. and rub it in topically.”
“Mag chloride is the best for absorption by mouth and through the skin. That works for anxiety and mood.”
“I take chloride.”
“a good quality magnesium supplement (look up magnesium oil) and iodine supplementation (Lugol's iodine solution) are good for you and mental functioning”
“Magnesium Chloride triggered... Because magnesium chloride is not high in bioavailability.”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate