PlainPill

Magnesium Aspartate

People mainly take Magnesium Aspartate for sleep, anxiety, recovery. Based on 9 first-hand reports and 3 meta-analyses & systematic reviews in the medical literature. Ranked #647 of 1,974 overall.

23
User score
Mostly positive
33% positive11% mixed11% negative44% unclear

Of reports that state an outcome, 60% are positive.

Clinical research
AStrong research base
3
meta-analyses
24
RCTs
161
papers

What Magnesium Aspartate does, according to users

Of the people who reported each effect, the share who said it got better.

3 more with fewer than 3 reports
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

Zhongguo Zhong Yao Za Zhi · 2021 · Meta-analysis / systematic review
[Systematic review and Meta-analysis of efficacy and safety of Compound Glycyrrhizin Injection in improving chronic hepatitis B liver damage]

Conclusion: Based on the results, CGI has a certain effect in improving CHB liver damage, but the evidence is not enough to prove that CGI would cause serious adverse events. In the future, more well-designed and strictly-enforced RCT with an adequate sample size are needed to further evaluate the effect CGI in alleviating CHB liver damage.

PubMed 33645037 ↗
Cochrane Database Syst Rev · 2018 · Meta-analysis / systematic review
Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users

Conclusion: Given the low or very low quality of the evidence for the reported outcomes, and the small number of trials identified with a limited number of participants for each comparison, it is not possible to draw firm conclusions regarding pharmacological interventions to facilitate benzodiazepine discontinuation in chronic benzodiazepine users. Due to poor reporting, adverse events could not be reliably assessed across trials. More randomised controlled trials are required with less risk of systematic errors ('bias') and of random errors ('play of chance') and better and full reporting of patient-cen

PubMed 29543325 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

500 mgbefore bed
450 mgnightly
nightlyas reported
1500-2000 mgnightly

Reported side effects

How often each side effect came up across all reports.

fatigue ×1muscle tension ×1jaw clenching ×1insomnia ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“Mag aspartate and Mag citrate-aspartate found in oxygen and energy promoting supplements”
Source discussion ↗
“Magnesium Aspartate 500mg”
Source discussion ↗
“Magnesium aspartate mostly causes long term (2 days) fatigue for me. It also seems to worsen my sleep.”
Source discussion ↗
“I'm honestly wary of getting Magnesium Aspartate, it's up to you if you think it's safe”
Source discussion ↗
“I can instantly tell when I'm not getting enough magnesium. I get jaw clenching, and muscle tension if I stop taking my nightly magnesium.”
Source discussion ↗
Top discussions (5)

Other options for sleep

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate